Overlap Syndrome between Primary Biliary Cholangitis and Primary Sclerosing Cholangitis
نویسندگان
چکیده
منابع مشابه
Primary sclerosing cholangitis and primary biliary cirrhosis.
Preview Although primary sclerosing cholangitis occurs most often in middle-aged or younger men and primary biliary cirrhosis in middle-aged or older women, the diseases have some traits in common-unfortunate ones. In both diseases, the cause is unknown, and liver transplantation is the only known effective therapy for advanced cases. Dr Fennerty discusses trials of medical treatments used in a...
متن کاملOverlap of primary biliary cirrhosis and primary sclerosing cholangitis – a rare coincidence or a new syndrome
BACKGROUND Overlap syndrome has been introduced to the field of hepatology to describe the coexistence of two or more autoimmune hepatic conditions in the same individual. This is a rare clinical case of a patient diagnosed with primary biliary cirrhosis (PBC) who later developed primary sclerosing cholangitis (PSC). This is a unique case as no other cases with a similar pattern have been repor...
متن کاملCurrent management of primary biliary cirrhosis and primary sclerosing cholangitis.
Primary biliary cirrhosis (PBC) is a chronic, cholestatic autoimmune liver disease characterized by inflammation and progressive destruction of interlobular bile ducts, ultimately leading to biliary cirrhosis. Population based studies have estimated the incidence of PBC as 19.1–251/ 1 000 000 in the general population [1,2]. The etiology of PBC is attributed to autoimmunity mainly due to the as...
متن کاملMedical treatment of primary biliary cirrhosis and primary sclerosing cholangitis.
Treatment of primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) with ursodeoxycholic acid (UDCA) has been in common use since 1985. In PBC, treatment with UDCA improves laboratory data, liver histology, enables a longer transplantation-free interval and prolongs disease survival. Because UDCA is unable to cure the disease newer drugs or combination therapies are still need...
متن کاملOverlap syndrome: autoimmune sclerosing cholangitis.
A 9-year-old-girl presented with clinical features of autoimmune hepatitis and associated signs of cholestasis in the form of itching and elevated levels of serum alkaline phosphatase. There was histologic evidence of bile duct injury. Hence a clinical diagnosis of "overlap syndrome" of autoimmune hepatitis with primary sclerosing cholangitis was considered.
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ژورنال
عنوان ژورنال: ACG Case Reports Journal
سال: 2018
ISSN: 2326-3253
DOI: 10.14309/crj.2018.54